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| Player Name | Team | Matches | Save | Clean Sheets | Time Played |
|---|---|---|---|---|---|
 Emil Audero | Cremonese | 34 | 125 | 11 | 3060 Mins |
| Elia Caprile | Cagliari | 38 | 122 | 8 | 3420 Mins |
| David de Gea | Fiorentina | 37 | 121 | 10 | 3330 Mins |
| Arijanet Muric | Sassuolo | 32 | 119 | 6 | 2880 Mins |
| Marco Carnesecchi | Atalanta | 37 | 115 | 13 | 3330 Mins |
| Wladimiro Falcone | Lecce | 38 | 110 | 10 | 3420 Mins |
| Mike Maignan | Milan | 37 | 108 | 13 | 3296 Mins |
| Mile Svilar | Roma | 38 | 107 | 18 | 3420 Mins |
| Lorenzo Montipo | Verona | 35 | 91 | 5 | 3150 Mins |
| Ivan Provedel | Lazio | 27 | 90 | 12 | 2430 Mins |
List of Serie A Top Saves All Seasons
| Player Name | Team | Matches | Save | Season | Time Played |
|---|---|---|---|---|---|
| Vanja Milinkovic-Savic | Torino | 37 | 135 | 2024-25 | 3330 Mins |
| Michele Di Gregorio | Monza | 33 | 127 | 2023-24 | 2874 Mins |
| Lorenzo Montipo | Verona | 38 | 134 | 2022-23 | 3420 Mins |
| Guglielmo Vicario | Empoli | 38 | 152 | 2021-22 | 3420 Mins |
| Andrea Consigli | Sassuolo | 37 | 131 | 2020-21 | 3330 Mins |
| Gabriel | Lecce | 34 | 157 | 2019-20 | 2998 Mins |
| Alessio Cragno | Cagliari | 38 | 155 | 2018-19 | 3420 Mins |
